Basic Information
VIS ID
TVIS44032271
Fusion event
HTLV-1-GRIN2A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
10171074/10169716 (Hg38)
End
10171074/10169716 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRIN2A
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-3915 ; hsa-mir-4710 ; hsa-mir-657 ; hsa-mir-3679-5p ; hsa-mir-3665 ; hsa-mir-1185-5p ; hsa-mir-3928-3p ; hsa-mir-125a-3p ; hsa-mir-583 ; hsa-mir-192-3p ; hsa-mir-6806-5p ; hsa-mir-5189-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-5589-3p ; hsa-mir-216a-5p ; hsa-mir-216b-5p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6840-3p ; hsa-mir-873-5p ; hsa-mir-1228-3p ; hsa-mir-3914 ; hsa-mir-6800-3p ; hsa-mir-1276 ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-3941 ; hsa-mir-2355-5p ; hsa-mir-136-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-148a-5p ; hsa-mir-3123 ; hsa-mir-3154 ; hsa-mir-3925-5p ; hsa-mir-411-5p ; hsa-mir-5010-3p ; hsa-mir-6770-5p ; hsa-mir-6832-5p ; hsa-mir-7515
Nearest miRNA
hsa-mir-1225/Upstream/4537150; hsa-mir-11401/Downstream/1136724;
Nearest TSS
ENST00000527434/Upstream/48140; ENST00000570163/Downstream/10287;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1076884, chr16-CpG: 282/Downstream/10370
Nearest cancer related gene
GRIN2A(TSG, No orient, 0)
Upstream sequence
agctgaggaaggcaaagtagaagaatgggaaggatctgagtcctcaatgtgacattaagtcactaagctagatctgaggctccttactaagcaaaaaact
Downstream sequence
gaatgtctttaatggtttaagacactgttggtcaaagactctgttacttgcacctgaaAGCACTCCAAACAACAGAAGAGgtataatggagctatcacct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate