Basic Information
VIS ID
TVIS44032272
Fusion event
HTLV-1-STXBP6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
NCBI36/hg18
Start
24504364/24965318 (Hg38)
End
24504364/24965318 (Hg38)
Orient
+
Location type
Intronic
Target gene
STXBP6
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4539
Nearest miRNA
hsa-mir-208a/Upstream/821753; hsa-mir-1185-1/Downstream/1943324;
Nearest TSS
ENST00000550708/Upstream/145841; ENST00000547786/Downstream/45322;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/535146, chr14-CpG: 125/Downstream/83900
Upstream sequence
AATGTAGGGAAGGAGAGGGAGAAAACCCCCAAGGCCAAGTCTGGGTTATCGTGTGATTTTGCTTCACATGACATGGGTCACGGATGCCTGTCATACATAC
Downstream sequence
ATATTAACATGTTTTTTCTTTTTGCTGTTGTCTTATAAATGTCTTGAGTCTGTTCCTGAGAGGCAGACTTTACGATTAGATTATTTTTATTTCAATGGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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