Basic Information
VIS ID
TVIS44032278
Fusion event
HTLV-1-MYO9B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
NCBI36/hg18
Start
17153319/17181510 (Hg38)
End
17153319/17181510 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
MYO9B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-484 ; hsa-mir-93-5p ; hsa-let-7e-5p ; hsa-mir-154-5p ; hsa-mir-6794-3p ; hsa-mir-615-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-4639-3p ; hsa-mir-4714-5p ; hsa-mir-193a-5p
Nearest miRNA
hsa-mir-10395/Upstream/1731902; hsa-let-7e/Downstream/1100567;
Nearest TSS
ENST00000633603/Upstream/865; ENST00000598464/Downstream/2227;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/8507, chr19-CpG: 25/Downstream/11251
Upstream sequence
CAGGGCATGCGATTTCCCAGAGAGGGTGGCCCTGATCTCTGCAGGTGGCCACATAAGCCAGTCAGGAGAGCCCAGAAGGTGCATAAACCGGTTTGGGATC
Downstream sequence
CCGACTGTTAGCACACTGTGGGATTGAGTAGTCTCTGCTTTCAGCCTGCAAATGGGGTAATGACTCTCATGCTTCCATTATGCTGACCCAGCACCAGGCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate