Basic Information
VIS ID
TVIS44032280
Fusion event
HTLV-1-C2CD3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
NCBI36/hg18
Start
73407558/74018865 (Hg38)
End
73407558/74018865 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
C2CD3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10392/Upstream/1235273; hsa-let-7a-2/Downstream/380372;
Nearest TSS
ENST00000527297/Upstream/9430; ENST00000542710/Downstream/15044;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/35108, chr11-CpG: 58/Downstream/151989
Upstream sequence
GCCCAGCCCTGAGAGGCAAATCCCAAATCTGACCTGCTCAGCCCGGCTGCCGCATGGCTCTGGTCTCATGCTCTGAGCTCACCCTCCATGCCTAAATTAG
Downstream sequence
AGGTCTGGTCATGTGGTTCTTATTACCGATATGCTCCCTCCGTGCCACACCCCACCTGATGCCACCCTCTCCTTACTCCAAGAAGCCTTCCCGGACAGGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate