Basic Information
VIS ID
TVIS44032286
Fusion event
HTLV-1-XKR9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
72128036/71053247 (Hg38)
End
72128036/71053247 (Hg38)
Orient
-
Location type
Intronic
Target gene
XKR9
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-7156-3p ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-1272 ; hsa-mir-8084 ; hsa-mir-3662 ; hsa-mir-3121-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-548l ; hsa-mir-1277-5p ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-6505-5p ; hsa-mir-4789-5p ; hsa-mir-7153-3p
Nearest miRNA
hsa-mir-124-1/Upstream/6673990; hsa-mir-10400/Downstream/3495296;
Nearest TSS
ENST00000518652/Upstream/382674; ENST00000521084/Downstream/102210;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/383832, chr8-CpG: 99/Downstream/494082
Upstream sequence
AAAAACCCTAAATTAACTTCTAAACAATAACCATTTTAGGagtggttccaacagaatggtgcatatctgaatcatttggagagttttgtgtgtgcacaca
Downstream sequence
ggcatgccctcagacatactgagtcattggatccggagtatagcctgggagtagagattctaaaaccccaggtgaatctgatgtgaagtcaaTGATTCTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate