Basic Information
VIS ID
TVIS44032299
Fusion event
HTLV-1-GLIS3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p24.2
Reference genome
NCBI36/hg18
Start
4280147/4290147 (Hg38)
End
4280147/4290147 (Hg38)
Orient
+
Location type
Intronic
Target gene
GLIS3
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-203a-3p ; hsa-mir-539-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-2355-3p ; hsa-mir-7159-3p ; hsa-mir-4482-3p ; hsa-mir-3679-3p ; hsa-mir-676-3p ; hsa-mir-431-5p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-138-2-3p ; hsa-mir-3655 ; hsa-mir-3667-3p ; hsa-mir-6734-3p
Nearest miRNA
hsa-mir-1302-9/Upstream/4259866; hsa-let-7a-1/Downstream/560150;
Nearest TSS
ENST00000422679/Upstream/137964; ENST00000440674/Downstream/8349;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/171553, chr9-CpG: 205/Downstream/7670
Upstream sequence
AAAGCAATGTTAACTCATCCATTCCAGAAAATTTCAAGAACATGACTTCCATAATGCCTATTTACAGCTAAAGGCCCTTTCTTAGTAAATATCATTAACA
Downstream sequence
GACCCATCTAGAGTCATAACTCATCTGATGAGCCAGTTAATTATTAATTTTCATACATCATTTCATTTCCTTAGGCTACATTTAGCCTTTGTTACATTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate