Basic Information
VIS ID
TVIS44032306
Fusion event
HTLV-1-LMX1A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
NCBI36/hg18
Start
163562120/165326259 (Hg38)
End
163562120/165326259 (Hg38)
Orient
-
Location type
Intronic
Target gene
LMX1A
miRNAs that regulate target gene
hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-342-3p ; hsa-mir-377-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-6868-3p ; hsa-mir-3182 ; hsa-mir-3120-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-362-3p ; hsa-mir-329-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2983619; hsa-mir-1182/Downstream/581662;
Nearest TSS
ENST00000473358/Upstream/107844; ENST00000294818/Downstream/29487;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/89989, chr1-CpG: 49/Downstream/26207
Upstream sequence
GTGGAAATGATGATTAAAGGAGCTAGAGACGGGGAGGAGGGGAAGGGGGGTAGATGAGATAGGGGAGAAGATATTTGGGTTTTGGACATGCCTGAGCTGT
Downstream sequence
CACTGAGTCCGATTTCCATATGATGGCTTCTGAGGATCAGTACTTCCCTGCACCCTCTAGGCAAGGCATGATTCTCCCAGGATCCACTAGGAATGTCTCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate