Basic Information
VIS ID
TVIS44032320
Fusion event
HTLV-1-ZNF521 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
21176967/25343005 (Hg38)
End
21176967/25343005 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF521
miRNAs that regulate target gene
hsa-mir-19b-3p
Nearest miRNA
hsa-mir-1-2/Upstream/1021259; hsa-mir-122/Downstream/1248462;
Nearest TSS
ENST00000575820/Upstream/20670; ENST00000415576/Downstream/8188;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/915962, chr18-CpG: 113/Downstream/6210
Upstream sequence
gtgaaagataagaatattagctaagaacacgtatgaaatgctggaaatTGTTTCTTGAAGTCAATATAAAGTTTAAAGCACAGTGATATTTTTTAGATTC
Downstream sequence
CAGGTCACAGAAACTCCTATAATATGGCAAGTTATAGTTTACTGTGTGGACTGTTCACCTCACTACAGGTTTCAACAAATGTATTTTGTATGAATATATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate