Basic Information
VIS ID
TVIS44032321
Fusion event
HTLV-1-FLT3LG integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
54675755/49480686 (Hg38)
End
54675755/49480686 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
FLT3LG
Nearest miRNA
hsa-mir-10395/Upstream/171818; hsa-let-7e/Downstream/20099;
Nearest TSS
ENST00000633603/Upstream/1769; ENST00000486930/Downstream/6868;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16092, chr19-CpG: 51/Downstream/6492
Upstream sequence
TGTGGAGCACTGACCTGGCCAAGGCCTCATCCTGGTGAGTCCTTCCTGGGCTATGGGGCCTGGACTTTGTGTCTGCAGGTTGGGAGGGTCACTAGGAGGC
Downstream sequence
CATGGAAGGGTGGTGAGCAGTGGAGGGGCAGGGGCAGCTCTAGGTGCAGAAAGACCCCTCTGGggccaggcgcggtggctcacgcctgtaatcccagcac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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