Basic Information
VIS ID
TVIS44032330
Fusion event
HTLV-1-KAT14 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
NCBI36/hg18
Start
18082553/18153909 (Hg38)
End
18082553/18153909 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
KAT14
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-501-5p ; hsa-mir-1250-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/7504214; hsa-mir-1-1/Downstream/316706;
Nearest TSS
ENST00000382410/Upstream/8810; ENST00000360010/Downstream/134374;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/15564, chr20-CpG: 67/Downstream/133991
Upstream sequence
acttaacatcaccatggtaagtgggaaacctatataaattgtcataagtagaatgtaacaataaaaataaaacaatgctgttaaattgtagctggatccc
Downstream sequence
atggcatataatggcaagccatggctttcttttccagtcaaaaagggaggctgctacaagtgttaatgagaatttaaagcagtaaactttcttttgatct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate