Basic Information
VIS ID
TVIS44032334
Fusion event
HTLV-1-ADCY2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p15.31
Reference genome
NCBI36/hg18
Start
7490351/7437238 (Hg38)
End
7490351/7437238 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADCY2
miRNAs that regulate target gene
hsa-mir-6833-5p ; hsa-mir-3190-3p ; hsa-mir-4680-5p ; hsa-mir-7114-5p ; hsa-mir-4539 ; hsa-mir-146a-3p ; hsa-mir-4714-5p ; hsa-mir-4318 ; hsa-mir-4643 ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-500b-3p ; hsa-mir-3922-5p
Nearest miRNA
hsa-mir-4277/Upstream/609317; hsa-mir-10397/Downstream/1023687;
Nearest TSS
ENST00000502646/Upstream/22574; ENST00000513693/Downstream/173871;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/40691, chr5-CpG: 112/Downstream/412594
Upstream sequence
TGCTGGACAGGACTTTTACAAAGTGCTGGTGTTCAACAGCAGCCCATGCATGTAAGGGATTGGCTTATGGGTGCTCAGCCTCCCCTGTGATCTTTTTCAG
Downstream sequence
CCCCCTCAAGCTACTACAGAGCTATGTAAAATGATGGTATTGGCTTTGCAAACCCAACTTTAAGACATGTTCCAGCCTCCCCTCCCGAGACAGGCTACCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate