Basic Information
VIS ID
TVIS44032336
Fusion event
HTLV-1-LRRC7 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
NCBI36/hg18
Start
69965577/69727306 (Hg38)
End
69965577/69727306 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LRRC7
Nearest miRNA
hsa-mir-101-1/Upstream/1543696; hsa-mir-11399/Downstream/1340325;
Nearest TSS
ENST00000473358/Upstream/158856; ENST00000415775/Downstream/32869;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/158494, chr1-CpG: 17/Downstream/192054
Upstream sequence
tggtgagccattagtggccaaccttctggcagctgggagaatgaatgattccatcctgcaagggatctgggatggtcagcacctcacagcttcCCAGGAG
Downstream sequence
AGAATGAAGAAAATGAATGTGAAGAATGCTTTGCTGTAAGGGGTTTTTATAATTATAGCCACTAATTCTCTCTTCCAAATTTTCCCCGCCATCATCTTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate