Basic Information
VIS ID
TVIS44032343
Fusion event
HTLV-1-CIR1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
174933665/174360691 (Hg38)
End
174933665/174360691 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
CIR1
Nearest miRNA
hsa-mir-128-1/Upstream/5777673; hsa-mir-10b/Downstream/806942;
Nearest TSS
ENST00000437798/Upstream/8728; ENST00000488349/Downstream/19989;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/16343, chr2-CpG: 67/Downstream/125945
Upstream sequence
TGATGGTAATAGGAAGAGTCATGTAAAAGAGAGTTATGACTGTGATTGGAGAATCATAATGCCCCTTTGAGATTATGGGAGGTGTAGCTTCCACTAGTAC
Downstream sequence
ATGCCTTTAACATCAAGCAGGGTCATTTACTGACAGAACAAGATTGTAATTAAAAATTTGTTCAAGTCAACAAAATTTCAAGGAACAGCCATGCTAACAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate