Basic Information
VIS ID
TVIS44032351
Fusion event
HTLV-1-FRYL integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p11
Reference genome
NCBI36/hg18
Start
48398526/48701752 (Hg38)
End
48398526/48701752 (Hg38)
Orient
-
Location type
Intronic
Target gene
FRYL
miRNAs that regulate target gene
hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-1261 ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-224-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3171 ; hsa-mir-3681-3p ; hsa-mir-3681-5p ; hsa-mir-376b-5p ; hsa-mir-376c-5p ; hsa-mir-6849-5p
Nearest miRNA
hsa-mir-12113/Upstream/1049009; hsa-mir-1243/Downstream/4010930;
Nearest TSS
ENST00000502981/Upstream/20581; ENST00000511662/Downstream/78377;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/210180, chr4-CpG: 121/Downstream/77562
Upstream sequence
CAAGTAAACTAATCCTTGTCAATAGACAGACTATTACATTTACTCTAGAAAGATACACGCTAAGAAGTCAGCTAAGCGGACAATGAGTCCAAAGGTATCT
Downstream sequence
CAGATAAAAGCAGAGGTGCATTCAAATACCTACACATTCATTATTTTATTGACCATTTTCTGCTACCTGGCGATCAAATATTTAATGCCCTGAATATGCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate