VISDB Viral Integration Site DataBase

VIS ID

TVIS44032354

Fusion event

HTLV-1-SPRY4 integration

Validated

No

Detection method

HTS

Data source

Curated

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

Chromosome

chr5

Cytoband

q31.3

Reference genome

Start

End

141677188/142317439 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6734-5p ; hsa-mir-4425 ; hsa-mir-625-5p ; hsa-mir-5187-5p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4764-5p ; hsa-mir-5093 ; hsa-mir-548v ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4670-3p ; hsa-mir-139-5p ; hsa-mir-4259 ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-3646 ; hsa-mir-129-5p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-4775 ; hsa-mir-4480 ; hsa-mir-590-3p ; hsa-mir-574-5p ; hsa-mir-6796-5p ; hsa-mir-6844 ; hsa-mir-4789-5p ; hsa-mir-223-5p ; hsa-mir-6742-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-3151-5p ; hsa-mir-491-5p ; hsa-mir-4697-3p ; hsa-mir-3650 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-6881-5p ; hsa-mir-4302 ; hsa-mir-6733-3p ; hsa-mir-6782-5p ; hsa-mir-4524b-3p ; hsa-mir-4672 ; hsa-mir-6867-5p ; hsa-mir-6768-5p ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-2355-5p ; hsa-mir-7848-3p ; hsa-mir-1236-3p ; hsa-mir-6892-3p ; hsa-mir-3162-3p ; hsa-mir-4267 ; hsa-mir-6796-3p ; hsa-mir-31-5p ; hsa-mir-411-5p ; hsa-mir-1233-5p ; hsa-mir-1249-5p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-185-3p ; hsa-mir-194-5p ; hsa-mir-196a-3p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-2114-3p ; hsa-mir-25-5p ; hsa-mir-3173-3p ; hsa-mir-342-5p ; hsa-mir-363-5p ; hsa-mir-4300 ; hsa-mir-4419a ; hsa-mir-4434 ; hsa-mir-4510 ; hsa-mir-4516 ; hsa-mir-4651 ; hsa-mir-4652-3p ; hsa-mir-4664-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4743-3p ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-541-3p ; hsa-mir-5591-5p ; hsa-mir-5703 ; hsa-mir-6085 ; hsa-mir-608 ; hsa-mir-6090 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-627-3p ; hsa-mir-654-5p ; hsa-mir-658 ; hsa-mir-664b-5p ; hsa-mir-6726-5p ; hsa-mir-6737-5p ; hsa-mir-6745 ; hsa-mir-6746-5p ; hsa-mir-6756-5p ; hsa-mir-6760-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6770-5p ; hsa-mir-6778-5p ; hsa-mir-6779-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6812-5p ; hsa-mir-6813-5p ; hsa-mir-6819-5p ; hsa-mir-6823-3p ; hsa-mir-6827-5p ; hsa-mir-6858-5p ; hsa-mir-6883-5p ; hsa-mir-6891-5p ; hsa-mir-8068 ; hsa-mir-891b ; hsa-mir-920 ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-10397/Upstream/1669513; hsa-mir-103a-1/Downstream/1362421;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/208085, chr5-CpG: 105/Downstream/6745

Nearest cancer related gene

SPRY4(TSG, No orient, 0)

Upstream sequence

CTGCCTGGAGGAAAGGGTGTGGCTTGGCCTAAGAATTAAAAATGCCACGGATAAGATTCTCCAGCACCAGCCAGAACCCTCACCCCCGGACAATGATAAC

Downstream sequence

ATGAGTCCCTTGTTCCAGAAACCGATGTCAGGAATATTCAGGGTCCTGCCAACACAATGTAGGCAGCAGTTTGAAGCTTCTATTGCCCCATATAGTTGGG