Basic Information
VIS ID
TVIS44032394
Fusion event
HTLV-1-PPP4R3A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
NCBI36/hg18
Start
91030833/91494736 (Hg38)
End
91030833/91494736 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP4R3A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-183-5p ; hsa-mir-30d-5p ; hsa-mir-642b-3p ; hsa-mir-4719 ; hsa-mir-642a-3p ; hsa-mir-3613-3p ; hsa-mir-425-5p ; hsa-mir-26b-5p ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-1260a/Upstream/14228446; hsa-mir-1185-1/Downstream/2453490;
Nearest TSS
ENST00000550708/Upstream/12738; ENST00000553427/Downstream/14911;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/75713, chr14-CpG: 164/Downstream/14590
Upstream sequence
tggatcacttgaggtcaggagttcgagaccagcctggccaaaatggtgaaaccccatctctactaaagacacacaaaaaattagctgggcatcgttgtgc
Downstream sequence
atgtctttaaacccagctactcaggaggctgaggcaggagaatcactttaacctgggaggtggaggttgcagtgagccaggattgcaccactgcacccca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate