Basic Information
VIS ID
TVIS44032395
Fusion event
HTLV-1-BRF1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
NCBI36/hg18
Start
104832330/105294948 (Hg38)
End
104832330/105294948 (Hg38)
Orient
-
Location type
Intronic
Target gene
BRF1
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1185-1/Upstream/144084; hsa-mir-4507/Downstream/326168;
Nearest TSS
ENST00000550708/Upstream/45544; ENST00000548265/Downstream/5520;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/22621, chr14-CpG: 188/Downstream/5273
Nearest cancer related gene
BRF1(TSG, No orient, 0)
Upstream sequence
ttcctcaacacaagcggctaattcaccccaggtgaaacacagcatcttaaatataactagaacctcagtgatgaaagaagccgaaaccacagtgcagaat
Downstream sequence
cttctgagaaagaaagctttgggaccagatggctacgctggtgaattctaccaaacatttcagaaagaaagaacaccaactctacataatgtcttccaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate