Basic Information
VIS ID
TVIS44032398
Fusion event
HTLV-1-TBC1D2B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
76123097/78043700 (Hg38)
End
76123097/78043700 (Hg38)
Orient
-
Location type
Intronic
Target gene
TBC1D2B
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-3915 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-3202 ; hsa-mir-3928-3p ; hsa-mir-5093 ; hsa-mir-194-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-1252-3p ; hsa-mir-6890-3p ; hsa-mir-603 ; hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/2281385; hsa-mir-11181/Downstream/1166088;
Nearest TSS
ENST00000557528/Upstream/18072; ENST00000409568/Downstream/10301;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/98958, chr15-CpG: 103/Downstream/33475
Upstream sequence
atattatttggccataaaaggaaatgaagcactgatagttgctacagcatggatgaatcttgaaaatattatgctaacggaaagaagccagacacaaagg
Downstream sequence
tatgcacggtgccatttatatgaaatgtccacaataaacaaattcataagccaggggcagtggctcatgtaatcccagcactttgggaggccaaggtagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate