Basic Information
VIS ID
TVIS44032400
Fusion event
HTLV-1-FMN1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
31142103/33062610 (Hg38)
End
31142103/33062610 (Hg38)
Orient
+
Location type
Intronic
Target gene
FMN1
miRNAs that regulate target gene
hsa-mir-136-3p ; hsa-mir-493-3p ; hsa-mir-432-5p ; hsa-mir-340-5p ; hsa-mir-219b-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-6504-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-3907 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6515-3p ; hsa-mir-1236-3p ; hsa-mir-6777-3p
Nearest miRNA
hsa-mir-1268a/Upstream/1997469; hsa-mir-10393/Downstream/1319459;
Nearest TSS
ENST00000557528/Upstream/136349; ENST00000634750/Downstream/5274;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/343115, chr15-CpG: 32/Downstream/132112
Upstream sequence
actcgggaggctgaggcaggagaatggcgtgaacctgggaggtggagcttgcagtgagccaagatggtgccactgcactccagcctgggcgacagagtga
Downstream sequence
gactccatctcaaaaaaaTAGTAATAATAATAATCGGAAAAGAACAGTAGTCTATAATGATTCAAATTCTATTTTTATTTTTCCACATTAAATTCATAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate