Basic Information
VIS ID
TVIS44032408
Fusion event
HTLV-1-SNTB1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
NCBI36/hg18
Start
121841246/120759825 (Hg38)
End
121841246/120759825 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
SNTB1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-24-3p ; hsa-mir-5011-5p ; hsa-mir-218-5p ; hsa-mir-510-3p ; hsa-mir-3606-5p ; hsa-mir-1825 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-8062 ; hsa-mir-1277-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p
Nearest miRNA
hsa-mir-12123/Upstream/1434560; hsa-mir-10400/Downstream/2455963;
Nearest TSS
ENST00000518652/Upstream/65917; ENST00000509350/Downstream/1428;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/314408, chr8-CpG: 121/Downstream/51350
Upstream sequence
ACTTCATAGCCTTTCATTCTGAACCACTCCGTTAAATTCTTATTTGGTTGGCCCTCTAGTGTTCCCCACAAGCCTAGAGTCTCCTTGAGAGAAGGCCTAT
Downstream sequence
GTCTTCACTCATCTCTAAATGTGAGGATCCTCTCCAGCCCTTGACAGGTGCCCATCATTTGATTTTCAACTCAAGCACAGTGTCAAGGGATTCAAACTTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate