Basic Information
VIS ID
TVIS44032418
Fusion event
HTLV-1-TRIQK integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
94046317/92964913 (Hg38)
End
94046317/92964913 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRIQK
miRNAs that regulate target gene
hsa-mir-3616-5p ; hsa-mir-573 ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-4635 ; hsa-mir-4662a-3p ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-5589-3p ; hsa-mir-4502 ; hsa-mir-4724-5p
Nearest miRNA
hsa-mir-12123/Upstream/1759354; hsa-mir-10400/Downstream/64838;
Nearest TSS
ENST00000518652/Upstream/4379; ENST00000522598/Downstream/575;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/820501, chr8-CpG: 56/Downstream/652
Upstream sequence
TCTCCAATTTACAGATAACGAAACAATTATTGCCCAAGGACAAACATTTCTTAACCATGCCAGTTTCCTGACTTGTAGGCCAATGCTCCTCCCAATGTTA
Downstream sequence
ACAAGCAGCACAAGCTTCCTTCCTGGGGGTTTGCACTGTAAACCTGCCAGAGGAAAATAAAAGATTTTTACCTCTTTTGTTTTTTCTCTCTGGAATGTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate