Basic Information
VIS ID
TVIS44032439
Fusion event
HTLV-1-TAPT1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
NCBI36/hg18
Start
15795446/16184725 (Hg38)
End
15795446/16184725 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
TAPT1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-193a-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-12113/Upstream/2556768; hsa-mir-12115/Downstream/4343550;
Nearest TSS
ENST00000502981/Upstream/5786; ENST00000573308/Downstream/2089;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/100613, chr4-CpG: 198/Downstream/41177
Upstream sequence
tggcactgtcaggctacaagagcagtcactctggagggtgtgcagtgctatctcattatggctttgtctttctccagtgacattttccctaataatgccg
Downstream sequence
agcagcttttcatgaccttattggacatttatagattttcttttgtgaaatgtctgttcaagccttttccccattttaaaactagattgtcctttcatta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate