Basic Information
VIS ID
TVIS44032441
Fusion event
HTLV-1-EGFLAM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
38315690/38279831 (Hg38)
End
38315690/38279831 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
EGFLAM
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-5089-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-4320 ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p
Nearest miRNA
hsa-mir-10397/Upstream/2131843; hsa-mir-103a-1/Downstream/277671;
Nearest TSS
ENST00000502646/Upstream/21166; ENST00000508868/Downstream/11155;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/20797, chr5-CpG: 151/Downstream/276289
Upstream sequence
agttagggtaatgctggctaaaggatacgtaactacaattagataggaataagctcaagagatctattgtacagcatgctgagtatagttaatgatgata
Downstream sequence
tattgtattattgaaaaatgctaagagtagatgttaagtgggcctaacatagtgataactatgtgaggtaatgcatttgttaactagctagatttaaccg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate