Basic Information
VIS ID
TVIS44032456
Fusion event
HTLV-1-NCAPG2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
NCBI36/hg18
Start
158181004/158695551 (Hg38)
End
158181004/158695551 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
NCAPG2
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-26b-5p ; hsa-mir-1260b ; hsa-mir-500a-3p ; hsa-mir-6771-5p ; hsa-mir-425-3p ; hsa-mir-7977 ; hsa-mir-6804-3p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-6746-5p ; hsa-mir-6739-3p ; hsa-mir-375 ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-4314 ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-6845-3p ; hsa-mir-4780 ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-217 ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-3612 ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4325 ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-6076 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6797-3p ; hsa-mir-6807-3p ; hsa-mir-6807-5p ; hsa-mir-6840-3p ; hsa-mir-767-5p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-10399/Upstream/103855;
Nearest TSS
ENST00000635602/Upstream/2212; ENST00000397143/Downstream/1100;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/107022, chr7-CpG: 94/Downstream/8915
Upstream sequence
CTGAAAAATCAACCCTGAAGAAATGAGAGTGAGAGAGGTTCCAGTAACAAACTATAGCAACAAAATGAGACACACACCCAGCTTCACTGAAGGCTGTTTG
Downstream sequence
GAGCTGGGGATGTGAGAAATGAGTGGCTGTTGCCTAGGGCACTGAAGAGCTGGCTGGAAGGGCAAGGAAAGGATGGGGGACAAAAGCTGTTCAAATATCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate