Basic Information
VIS ID
TVIS44032463
Fusion event
HTLV-1-ARHGAP31 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
120604672/119403135 (Hg38)
End
120604672/119403135 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP31
miRNAs that regulate target gene
hsa-mir-6770-3p ; hsa-mir-6825-5p ; hsa-mir-4730 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-663a ; hsa-mir-6787-5p ; hsa-mir-1908-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6760-5p ; hsa-mir-3680-3p ; hsa-mir-576-5p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-4735-5p ; hsa-mir-133a-5p ; hsa-mir-138-5p ; hsa-mir-3189-5p ; hsa-mir-3692-5p ; hsa-mir-4758-3p ; hsa-mir-544a ; hsa-mir-548q ; hsa-mir-5699-5p ; hsa-mir-6071 ; hsa-mir-6131 ; hsa-mir-6738-3p ; hsa-mir-6828-3p ; hsa-mir-93-3p
Nearest miRNA
hsa-let-7g/Upstream/2552768; hsa-mir-12124/Downstream/681429;
Nearest TSS
ENST00000440867/Upstream/78243; ENST00000390401/Downstream/33681;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/844, chr3-CpG: 53/Downstream/65765
Upstream sequence
ttgagtcTCTGGGTGTGTCTGGAGTGAAGAGAGTTTCTTTAATTAACAAGCAAACATGGGCCACATAAAATGGAAGCAGGGAGAACCCCAAAGGAAAGGG
Downstream sequence
TGGCTGACAATCAAACCAACAAATGTTTATTGTGATTTAGGAATGTTTCTTTTCCGTTAATATTAGTcattttcagcacctattaggttgtcaggcactc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate