Basic Information
VIS ID
TVIS44032481
Fusion event
HTLV-1-IBTK integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
NCBI36/hg18
Start
82964386/82197950 (Hg38)
End
82964386/82197950 (Hg38)
Orient
+
Location type
Intronic
Target gene
IBTK
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-185-5p ; hsa-mir-16-5p ; hsa-mir-6781-3p ; hsa-mir-3692-3p ; hsa-mir-6083 ; hsa-mir-627-3p ; hsa-mir-140-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-10398/Upstream/3658641; hsa-mir-1202/Downstream/8114792;
Nearest TSS
ENST00000381078/Upstream/6096; ENST00000535040/Downstream/7979;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/443862, chr6-CpG: 49/Downstream/49332
Upstream sequence
ACACAGATGTTAAGCTTTTACGCAACTGTCTTTGATGAAATTGGCCTCATACTCAAATTTTCTTCCTTAACAGGTCTTTTTGGCCTCCAATTAAATCTGA
Downstream sequence
CCTTTTAGTTATCTTTGACTACAGATATCCTGGCCACAGAAAGAACAGTACACcaggaaaatacggacctggaatcaagagaacaaattttatttctttt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate