Basic Information
VIS ID
TVIS44032488
Fusion event
HTLV-1-SMAP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
NCBI36/hg18
Start
71464726/70698302 (Hg38)
End
71464726/70698302 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
SMAP1
miRNAs that regulate target gene
hsa-mir-25-3p
Nearest miRNA
hsa-mir-10398/Upstream/13308090; hsa-mir-10524/Downstream/678658;
Nearest TSS
ENST00000381078/Upstream/29772; ENST00000445046/Downstream/74627;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/29827, chr6-CpG: 177/Downstream/257355
Upstream sequence
cagcacttaaaatatgtcatatcactttctcctggcctgtaaggtttccactgagacatatgctgccagatgtgttagagctcctttgtatgttacttgt
Downstream sequence
ttcttttctcttgcttcttttaggatcctttatctttgacatttaggaatttggtaattaaatgtctcgaggtagtcttatttcggttaaatctgtaacc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate