Basic Information
VIS ID
TVIS44032502
Fusion event
HTLV-1-STARD13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
32612830/33140693 (Hg38)
End
32612830/33140693 (Hg38)
Orient
+
Location type
Intronic
Target gene
STARD13
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-122-5p ; hsa-mir-4452 ; hsa-mir-3658 ; hsa-mir-1231 ; hsa-mir-183-3p ; hsa-mir-516b-5p ; hsa-mir-4276 ; hsa-mir-4653-3p ; hsa-mir-219a-1-3p ; hsa-mir-570-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-148a-3p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-9-5p
Nearest miRNA
hsa-mir-2276/Upstream/8978189; hsa-mir-1267/Downstream/6523341;
Nearest TSS
ENST00000623511/Upstream/27500; ENST00000442716/Downstream/45386;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/123403, chr13-CpG: 88/Downstream/209100
Nearest cancer related gene
STARD13(TSG, No orient, 0)
Upstream sequence
AAGGTGAGGTCCACTAAAATTCATTTGATCTTCTTTTTTTTTGGTGTTATTTTACAGCAGAAATTCAGATTAAAGTTATTTTCAAAGATTAGGTTACTAA
Downstream sequence
GGGGTAACTTAAAATCCTTTGGCTTTAATGATTTCTCTGTGTAGACCAGGATAAAAACACtttcttttctttcttttttttttttttgaggcggagtctc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate