Basic Information
VIS ID
TVIS44032507
Fusion event
HTLV-1-CDK13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
40011125/40005001 (Hg38)
End
40011125/40005001 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDK13
miRNAs that regulate target gene
hsa-mir-133b ; hsa-mir-29b-2-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-664a-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-6794-3p ; hsa-mir-376a-5p ; hsa-mir-372-5p ; hsa-mir-888-5p
Nearest miRNA
hsa-mir-1183/Upstream/3085569; hsa-mir-10399/Downstream/3145894;
Nearest TSS
ENST00000635602/Upstream/5612; ENST00000642592/Downstream/40929;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/52988, chr7-CpG: 109/Downstream/129281
Upstream sequence
taaacctgtaatcccagcacttagggaaggccgaggtaggtggatcacccgactgaggtcaagagttgtttgagaccagcctggccaacatggtgaaacc
Downstream sequence
catctcaactaaaaatacaaaaattagccaggcatggtggtgcatgcctatagtcccagctactcaggaggctgaagcaggagaattgtttgaacctggg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate