Basic Information
VIS ID
TVIS44032511
Fusion event
HTLV-1-IMMP2L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
110961646/111534354 (Hg38)
End
110961646/111534354 (Hg38)
Orient
+
Location type
Intronic
Target gene
IMMP2L
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-587 ; hsa-mir-3180-5p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6815-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-103a-2-5p ; hsa-mir-3188 ; hsa-mir-770-5p ; hsa-mir-4712-5p
Nearest miRNA
hsa-mir-10525/Upstream/9062823; hsa-mir-10399/Downstream/3118991;
Nearest TSS
ENST00000635602/Upstream/12907; ENST00000452714/Downstream/27547;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2963892, chr7-CpG: 68/Downstream/27669
Upstream sequence
aacaaccaaatgttcacaaatatgtaaataaattatgacatgcatacagtagagtaatctgcaatcattaaaaagaaCAATATATCGTTATATTGCTTGA
Downstream sequence
GATTCTCCTCCAAAAAAGTTGGAAAATTGCATTTTTAATATGAACCCATTTATGTGAAATTTTATACACACACAGcatcatcctcatcgtcatccttatc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate