Basic Information
VIS ID
TVIS44032523
Fusion event
HTLV-1-PEBP4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
22844289/22930831 (Hg38)
End
22844289/22930831 (Hg38)
Orient
+
Location type
Intronic
Target gene
PEBP4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-124-1/Upstream/685794; hsa-mir-10400/Downstream/2022965;
Nearest TSS
ENST00000518652/Upstream/2923; ENST00000518534/Downstream/10505;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/64792, chr8-CpG: 82/Downstream/68456
Upstream sequence
TCAAACCTGATCTTTCTCTTGGGGATTTTCAGGACTTTGATTCATACTTGAAACCTAAGATCTGAAAGCCGTGTTCAAGCTTGCGGAGTGACAATTCTCC
Downstream sequence
CTCCCCATCACCACCCCGGCTCCTGGAAAGTCCCATTGCTAGATTTCTTGGTGCCCACCCTTGAAGTCCCCCTCTCTTCCTTCAGTTACCTGGGCTGGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate