Basic Information
VIS ID
TVIS44032524
Fusion event
HTLV-1-VPS13B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
NCBI36/hg18
Start
100326235/99244831 (Hg38)
End
100326235/99244831 (Hg38)
Orient
-
Location type
Intronic
Target gene
VPS13B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-30e-5p ; hsa-mir-186-5p ; hsa-mir-3613-5p ; hsa-mir-4494 ; hsa-mir-499b-5p ; hsa-mir-4705
Nearest miRNA
hsa-mir-12123/Upstream/851093; hsa-mir-10400/Downstream/291805;
Nearest TSS
ENST00000518652/Upstream/88202; ENST00000522802/Downstream/30378;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/231060, chr8-CpG: 35/Downstream/648598
Upstream sequence
AACTTATGAGAGTCTGAATCAGCAAAGTTATTTTTCATCAGTATTAGTCCATATAAGTGCCTACTCATTAAACTAAACAGGAAGAAGGACTATATTACAT
Downstream sequence
TAGCTAAATGAGTACCTCATGACTGAAGATAGACACACACAAAGTTTAGATATTTAAAATATGTGTACATGTGTGGTGCATGGATGCATGTATGTGTAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate