Basic Information
VIS ID
TVIS44032526
Fusion event
HTLV-1-ARID1B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
NCBI36/hg18
Start
157428766/157065940 (Hg38)
End
157428766/157065940 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARID1B
miRNAs that regulate target gene
hsa-mir-92b-3p ; hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-578 ; hsa-mir-643 ; hsa-mir-138-2-3p ; hsa-mir-5692a ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-mir-3143 ; hsa-let-7a-3p ; hsa-mir-656-3p ; hsa-mir-144-3p ; hsa-mir-602 ; hsa-mir-543
Nearest miRNA
hsa-mir-10398/Upstream/286209; hsa-mir-1913/Downstream/463192;
Nearest TSS
ENST00000381078/Upstream/29625; ENST00000493658/Downstream/18826;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/43682, chr6-CpG: 105/Downstream/170097
Upstream sequence
ATGTAAGTAttgtggaggtgtaacataaatacagggacatgcacaaatttaaatgtacaacttgatacattttctcaaaatgaacacacttgtgtaatca
Downstream sequence
gtacttggttcagaaacaccaccaggaccccaaaagccctcttatgcctcttttgaatcattatccATCCATCCCCAACCCCTACCACACTGTCTGAATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate