Basic Information
VIS ID
TVIS44032539
Fusion event
HTLV-1-AGFG2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
99982501/100546942 (Hg38)
End
99982501/100546942 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
AGFG2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-324-3p ; hsa-let-7b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p
Nearest miRNA
hsa-mir-10525/Upstream/190221; hsa-mir-10399/Downstream/321094;
Nearest TSS
ENST00000635602/Upstream/7717; ENST00000429987/Downstream/3484;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/7350, chr7-CpG: 98/Downstream/22571
Upstream sequence
AAATGTGATCGGAAGACAGTCTTCGGGGCAGACCAAGCTTAAGAGCTATTGTTTGATATGTAGTAACAAAGCCTTGCTTTCGTTTTTCCCTGAGCTTATC
Downstream sequence
TTTCCTTGGGGGCATCAGTCCTCTTTGATATTGCTTGTCTTTTATAAGAGCATTTTTGAGACCCTTTATACCTAAAGGTCTAGCAGCAGAATTGCTGCAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate