Basic Information
VIS ID
TVIS44032550
Fusion event
HTLV-1-ANK2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
NCBI36/hg18
Start
114405951/113265346 (Hg38)
End
114405951/113265346 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANK2
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-647
Nearest miRNA
hsa-mir-12113/Upstream/112984; hsa-mir-1305/Downstream/1391413;
Nearest TSS
ENST00000502981/Upstream/90930; ENST00000502701/Downstream/27636;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/558995, chr4-CpG: 86/Downstream/495567
Upstream sequence
GACTGATATTTTAATACTGTTTTAACCTCGGAAAGCACTTTCTCATATCTCTTTATTTTCATGAATTTTAAAATTTAACCTAAAGTATTTAGATGCTATA
Downstream sequence
CATATTAAAATTTATTTCTTACCACTTAAACCAATCACATTTCCACAGTCATCCCTCACTAGTTACATAAAATCAAGTTATTCTCCAAGTTTTAGTGTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate