Basic Information
VIS ID
TVIS44032553
Fusion event
HTLV-1-C12orf76 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
NCBI36/hg18
Start
108972354/110050166 (Hg38)
End
108972354/110050166 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
C12orf76
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-10a-5p
Nearest miRNA
hsa-let-7i/Upstream/216730; hsa-mir-1178/Downstream/1253976;
Nearest TSS
ENST00000382841/Upstream/881; ENST00000549009/Downstream/9012;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1397, chr12-CpG: 45/Downstream/74167
Upstream sequence
tacaactcggtgtctgagaggttttgtctgcggctcgtcctgctacaAGACTAGAAGAGTAGCATATTATATTCAGTAACTGTTTGCTGAatacatgagg
Downstream sequence
gaattgagctaagtgtttggcccaacactgcacacacaaagtggcagagctagaatttgacccaagcatagttttgaatctggaggctttaccacctcac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate