Basic Information
VIS ID
TVIS44032577
Fusion event
HTLV-1-CD81 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
NCBI36/hg18
Start
2358213/2380407 (Hg38)
End
2358213/2380407 (Hg38)
Orient
-
Location type
Intronic
Target gene
CD81
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-423-5p ; hsa-mir-769-3p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-582-5p ; hsa-mir-1265 ; hsa-mir-6504-3p ; hsa-mir-8070 ; hsa-mir-3937 ; hsa-mir-4672 ; hsa-mir-4789-5p ; hsa-mir-6768-5p ; hsa-mir-3152-3p ; hsa-mir-5702 ; hsa-mir-6126 ; hsa-mir-6864-5p ; hsa-mir-4493 ; hsa-mir-605-3p ; hsa-mir-552-3p ; hsa-mir-8080 ; hsa-mir-101-3p ; hsa-mir-190a-3p
Nearest miRNA
hsa-mir-210/Upstream/207269; hsa-let-7a-2/Downstream/1475655;
Nearest TSS
ENST00000527297/Upstream/1251; ENST00000493525/Downstream/2053;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2039, chr11-CpG: 25/Downstream/5074
Upstream sequence
AGTTCCATTTTAGAGAGGAAAGAGGCCTTGCCTGTGGGAGAAGGCAGCTGGGGTAGCCTGACCTCTTTCCCAGGAAGGAGCCcacacacacacgcacagg
Downstream sequence
cactcacacacacgaatgtgcacacacacacactcccaccttcacacacactcacacTCTTGCTGTCTCCCTTCCCAAGCCAAGGTGCGAGGGGGAAGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate