Basic Information
VIS ID
TVIS44032583
Fusion event
HTLV-1-LRRFIP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p22.2
Reference genome
NCBI36/hg18
Start
37192224/37175729 (Hg38)
End
37192224/37175729 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRFIP2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-3692-3p ; hsa-mir-6792-5p ; hsa-mir-922 ; hsa-mir-4719 ; hsa-mir-577 ; hsa-mir-3163 ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-12127/Upstream/1431170; hsa-let-7g/Downstream/793675;
Nearest TSS
ENST00000440867/Upstream/514; ENST00000607744/Downstream/328;
Nearest CpG islands
chr3-CpG: 99/Target, None/Upstream, None/Downstream
Upstream sequence
AGGAGGAAGAAGTAAAATTCCCAAAAAATGCTACGCCCTACACCGTCCTGACACCGTTCCCTGGGGGTGCTCGTCCTGGGACAGAACCGTAGTGTGGCGT
Downstream sequence
CTAAGGAGGAAGAGAAGGCGCCTAGGGCACCCGAAACGGAGGGACAGCTGCCCAATTTAATTTCTCCCACAGTGGGAATAACACGTACCTTTTCCCCAGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate