Basic Information
VIS ID
TVIS44032585
Fusion event
HTLV-1-SLC2A13 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
38695554/40015485 (Hg38)
End
38695554/40015485 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC2A13
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-381-3p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4705 ; hsa-mir-6826-5p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/14141406; hsa-let-7i/Downstream/2308215;
Nearest TSS
ENST00000382841/Upstream/143604; ENST00000457989/Downstream/90374;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/571788, chr12-CpG: 108/Downstream/89675
Upstream sequence
CTCTGACATCAAGATCCTGTTAATAATTAGGTCTCTGGCCAGTTTACCTGAGTAGCTTACTAATTCACTTGGCAGGTAGAGCTTCTCAGCACAAATTTTC
Downstream sequence
CTTTTGAATAAAACTAAAGGCAAATGTATGTCTGGGTTTCCTTTCTGGAAATGTACTACcacttcctccagtctcagagggcacctcatcaaaagggcca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate