Basic Information
VIS ID
TVIS44032598
Fusion event
HTLV-1-DIAPH3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
59384715/59912580 (Hg38)
End
59384715/59912580 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
DIAPH3
miRNAs that regulate target gene
hsa-mir-155-5p
Nearest miRNA
hsa-mir-1297/Upstream/4738032; hsa-mir-1267/Downstream/1287218;
Nearest TSS
ENST00000623511/Upstream/51148; ENST00000435636/Downstream/100171;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2277784, chr13-CpG: 52/Downstream/250946
Upstream sequence
AAGTAAGCCACACACTTAAACAACAGAACTACTTGAATAAAGATTAAAGGAATACACAAGACTATGTCTTCCTGATACAACTTAAATGATTAAACAATCC
Downstream sequence
CTTGGACAAAGTCTATATCGATCCTCTGTATCAAAATACAATCAACTATAATAGCGTTACAAGAAGTTAGTGCATTGATATTAAAATTAAGATAAAAAAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate