Basic Information
VIS ID
TVIS44032600
Fusion event
HTLV-1-SYNE1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q25.2
Reference genome
NCBI36/hg18
Start
152676137/152313309 (Hg38)
End
152676137/152313309 (Hg38)
Orient
+
Location type
Intronic
Target gene
SYNE1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-148b-3p ; hsa-mir-9-5p ; hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10398/Upstream/1210533; hsa-mir-1202/Downstream/2540051;
Nearest TSS
ENST00000381078/Upstream/2142; ENST00000412161/Downstream/5035;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/10964, chr6-CpG: 64/Downstream/323366
Upstream sequence
ttttgttcttaagataccaggatatcaggacattgcctgagtctgttatttcccagatctattaaggcctgggtatcttcagttagcattatcaacctgt
Downstream sequence
ctaaccataattattctgtgactaagaatgcctgacgtgggaatgctacccaataggtgtcatcctcatttacccagcccctattcaggcccctacgaag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate