Basic Information
VIS ID
TVIS44032602
Fusion event
HTLV-1-WIF1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q14.3
Reference genome
NCBI36/hg18
Start
63794378/65114331 (Hg38)
End
63794378/65114331 (Hg38)
Orient
+
Location type
Intronic
Target gene
WIF1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-374a-5p ; hsa-mir-181a-5p ; hsa-mir-203a-3p
Nearest miRNA
hsa-let-7i/Upstream/491726; hsa-mir-1178/Downstream/909289;
Nearest TSS
ENST00000382841/Upstream/47672; ENST00000541171/Downstream/6355;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/288968, chr12-CpG: 84/Downstream/6767
Nearest cancer related gene
WIF1(TSG, No orient, 0)
Upstream sequence
TAAGTCTCTAACTCCAGTCCAACGGGAAACTTGAGAGTGCAAACTGTAGCCAATTTAATGGGACCAGTGTTACATCACATCAAACACCATATTACAGAAA
Downstream sequence
CAGATCAGTAGGATGATTCTGTTTTTTATAAAATTAGCAAATATGTGAGTCCATTGTCAGAGAAATGGCCTGTTTCTGTTTTCCCTTTTTTCCAGTGGTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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