Basic Information
VIS ID
TVIS44032603
Fusion event
HTLV-1-NFIB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
End
14365133/14375134 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-92a-3p ; hsa-mir-548c-3p ; hsa-mir-4668-3p ; hsa-mir-1277-5p ; hsa-mir-590-3p ; hsa-mir-19a-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-5011-5p ; hsa-mir-3714 ; hsa-mir-548aw ; hsa-mir-190a-3p ; hsa-mir-335-3p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4517 ; hsa-mir-605-3p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-20a-5p ; hsa-mir-6857-5p ; hsa-mir-491-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-92a-2-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-4450 ; hsa-mir-3134 ; hsa-mir-6134 ; hsa-mir-1197 ; hsa-mir-6757-3p ; hsa-mir-3924 ; hsa-mir-656-3p ; hsa-mir-4775 ; hsa-mir-512-3p ; hsa-mir-4803 ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302e ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-3912-5p ; hsa-mir-6748-3p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-605-5p ; hsa-mir-339-5p ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-6773-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-1228-3p ; hsa-mir-3185 ; hsa-mir-1246 ; hsa-mir-129-5p ; hsa-mir-3672 ; hsa-mir-4524a-3p ; hsa-mir-6864-3p ; hsa-mir-8055 ; hsa-mir-431-5p ; hsa-mir-5691 ; hsa-mir-624-3p ; hsa-mir-6805-3p
Nearest miRNA
hsa-mir-101-2/Upstream/8367230; hsa-let-7a-1/Downstream/4198172;
Nearest cancer related gene
NFIB(OG, No orient, 0)
Upstream sequence
GCTTCCTCCCAAAGGAGAGAAGTAGTTTGTTCAGTAAGGATTTGTATTTAACTGGCAGTAACAGAGACCAGACTTCAATGTCTTAAACATCCAAGACTTA
Downstream sequence
TTCCCAACATAAGAGAAACTCTACCTCTGGATGCAcagggctcatatagtggttcctcagagtcatcagagccctaggctctttctatctctctgctctt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate