Basic Information
VIS ID
TVIS44032609
Fusion event
HTLV-1-GNAI1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
NCBI36/hg18
Start
79616412/80149160 (Hg38)
End
79616412/80149160 (Hg38)
Orient
+
Location type
Intronic
Target gene
GNAI1
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-1-3p ; hsa-mir-320a ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-9-3p ; hsa-mir-4719 ; hsa-mir-8485 ; hsa-mir-676-5p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-409-5p
Nearest miRNA
hsa-mir-10525/Upstream/4233891; hsa-mir-10399/Downstream/12054855;
Nearest TSS
ENST00000635602/Upstream/13405; ENST00000447650/Downstream/37899;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/13587, chr7-CpG: 59/Downstream/769830
Upstream sequence
GCTATACTGTGGACATTTAGGGAAGCAAACATTTGAGTAAATTTCTTTTCTCGATGTATTTTGAGTGGTTGATGTTGTATTGCAAATGTAACtttacact
Downstream sequence
tattctggcttaaatatttacttattaaatattttctgtaaatcccaactttagtggctatatatgttttacagatattccataatttgtttaatcacac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate