Basic Information
VIS ID
TVIS44032611
Fusion event
HTLV-1-PRKG1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
53463502/52033736 (Hg38)
End
53463502/52033736 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
PRKG1
miRNAs that regulate target gene
hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-3591-5p ; hsa-mir-1273e ; hsa-mir-921 ; hsa-mir-3606-5p
Nearest miRNA
hsa-mir-1265/Upstream/734081; hsa-mir-107/Downstream/2574138;
Nearest TSS
ENST00000439456/Upstream/334145; ENST00000646354/Downstream/13012;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/333737, chr10-CpG: 64/Downstream/280493
Upstream sequence
TGAATTCAGAAACTCTAAAGTATATGTAAAGCAGGAGCTGTTGGGGGAGGGAGGATTATGAAAGTAGTGCAGGAGTGTTTCTAGGGCTTCTACTAAGTGG
Downstream sequence
GTTTGCACAAGTGGTAAATTtcatgcacgtccgtgtgaacagaccaccaaacaggctttgtgtgagcaacatggctgtttatttcacccgggtgcaggcg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate