Basic Information
VIS ID
TVIS44032626
Fusion event
HTLV-1-CHD1L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
145183133/147244857 (Hg38)
End
145183133/147244857 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
CHD1L
miRNAs that regulate target gene
hsa-mir-320a
Nearest miRNA
hsa-mir-101-1/Upstream/1394212; hsa-mir-1182/Downstream/1089622;
Nearest TSS
ENST00000473358/Upstream/1807; ENST00000485113/Downstream/26047;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1229, chr1-CpG: 81/Downstream/354599
Nearest cancer related gene
CHD1L(OG, No orient, 0)
Upstream sequence
tgtaccatagtttagacagtccctcttcttggtatttaggttctttttttttgctattgtaagtaacataaatatccttgtaaccaaatatttattatag
Downstream sequence
gtatggacgtttaattcctgaaaggtaccatttctagaataaagagtatgcaaaatttttGCTTATTTCTCTATACTCTCAGCAACACTGGTATTTTCTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate