Basic Information
VIS ID
TVIS44032631
Fusion event
HTLV-1-RERE integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.23
Reference genome
NCBI36/hg18
Start
8802173/8819527 (Hg38)
End
8802173/8819527 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
RERE
miRNAs that regulate target gene
hsa-mir-200b-3p ; hsa-mir-429 ; hsa-mir-92b-3p ; hsa-mir-301a-3p ; hsa-mir-320a ; hsa-mir-4681 ; hsa-mir-4722-3p ; hsa-mir-4763-5p ; hsa-mir-4769-3p ; hsa-mir-596 ; hsa-mir-6501-3p ; hsa-mir-6727-3p ; hsa-mir-6817-5p
Nearest miRNA
hsa-mir-12136/Upstream/2389631; hsa-mir-101-1/Downstream/46975;
Nearest TSS
ENST00000473358/Upstream/1884; ENST00000442636/Downstream/52049;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1523, chr1-CpG: 112/Downstream/58727
Nearest cancer related gene
RERE(OG, No orient, 0)
Upstream sequence
AATAAACTGCTTCCAACATTCTAGATATGGATAGGACTATCTGACTTCCTGTTTGGAAATGATGAGGGATAAAGTATATCAGTTAGATGGCTTCACTTTC
Downstream sequence
CATCAAAATCTCTATCTACAGGAGCAttctttcttttttttcttttttttttttttgagacagagtctcgctctgttgcccaggctggagtgcagtggca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate