Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene160688667160272151160493794160471848160475754160435481160437869160432094160434281160454601160454800160431570160431719160469290160469439160480409
Basic Information
VIS ID
TVIS44032634
Fusion event
HTLV-1-RBMS1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
NCBI36/hg18
Start
161045166/160480409 (Hg38)
End
161045166/160480409 (Hg38)
Orient
+
Location type
Intronic
Target gene
RBMS1
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-1249-3p ; hsa-mir-4662a-5p ; hsa-mir-325 ; hsa-mir-3976 ; hsa-mir-6856-5p ; hsa-mir-6758-5p
Nearest miRNA
hsa-mir-128-1/Upstream/72527; hsa-mir-10b/Downstream/8102534;
Nearest TSS
ENST00000437798/Upstream/64231; ENST00000477952/Downstream/12560;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/72377, chr2-CpG: 100/Downstream/12303
Upstream sequence
TGCAAGAAAAATTAAAAAGAACGTCATCTGTTCTTAAAGAGTAGGTTTCAGTGGCAAGCTCCTTTTCAAAATTAATTTTGATCTGTGATAACAAACATAC
Downstream sequence
TCTCTCTCTTCAAAAGAATTATTTTCTTCATAGAACCTATGCCAACTACCATAATACAGATCTTGAAGAAATCATTGGATGTATTTAAGAAACAAGTACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate