Basic Information
VIS ID
TVIS44032653
Fusion event
HTLV-1-VOPP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
55585543/55550356 (Hg38)
End
55585543/55550356 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
VOPP1
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-320b ; hsa-mir-877-3p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-15b-5p ; hsa-mir-431-5p ; hsa-mir-5581-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-1343-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-374b-3p ; hsa-mir-424-5p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-4690-3p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-5685 ; hsa-mir-646 ; hsa-mir-6783-3p ; hsa-mir-6838-5p ; hsa-mir-938
Nearest miRNA
hsa-mir-1183/Upstream/10668556; hsa-mir-10399/Downstream/1405429;
Nearest TSS
ENST00000635602/Upstream/10729; ENST00000454777/Downstream/2496;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/100800, chr7-CpG: 144/Downstream/21228
Upstream sequence
GGCAGGTGCCACCCTCTGGAGAGAAAATCTGCCAACACAGATTGTAAACAAACGTACCTAAGTGTACATAAATAAGGGCGAAGATCCAAACCTTGTAACA
Downstream sequence
CAGGCAACACTTATTTTTGCCCTAAGAAACAATGATAGAATATTTAACTCCATGGtctcgtacactgctggagggaatataaatttggtttgaaaaaagc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate