Basic Information
VIS ID
TVIS44032661
Fusion event
HTLV-1-ACTA2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
NCBI36/hg18
Start
90711889/88962152 (Hg38)
End
90711889/88962152 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
ACTA2
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-1265/Upstream/1458198; hsa-mir-107/Downstream/101183;
Nearest TSS
ENST00000439456/Upstream/9379; ENST00000460510/Downstream/28430;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/81286, chr10-CpG: 68/Downstream/28384
Upstream sequence
gatgactgaaaaggccaagtggtacttctgataaacagaggacctaggtctcctgcaagggattggccaccactcagccccatctgttgttgtaatgcta
Downstream sequence
gttcagagttgccagatcttccactttttatgagaaggtagaaattgtaacctttgtgcaaaaatcccttcatttaaaatgatggcaattaactaacatt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate